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Hypoxia Induces Permeability and Giant Cell Responses of Andes Virus-Infected Pulmonary Endothelial Cells by Activating the mTOR-S6K Signaling Pathway

Andes virus (ANDV) is a South American hantavirus that causes a highly lethal hantavirus pulmonary syndrome (HPS) characterized by hypoxia, thrombocytopenia, and vascular leakage leading to acute pulmonary edema. ANDV infects human pulmonary microvascular and lymphatic endothelial cells (MECs and LE...

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Autors principals: Gavrilovskaya, Irina N., Gorbunova, Elena E., Mackow, Erich R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838155/
https://ncbi.nlm.nih.gov/pubmed/24067973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02103-13
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