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Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection

Reovirus encephalitis in mice was used as a model system to investigate astrocyte activation (astrogliosis) following viral infection of the brain. Reovirus infection resulted in astrogliosis, as evidenced by increased expression of glial fibrillary acidic protein (GFAP), and the upregulation of gen...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Clarke, Penny, Zhuang, Yonghua, Berens, Heather M., Leser, J. Smith, Tyler, Kenneth L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498044/
https://ncbi.nlm.nih.gov/pubmed/30814290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02027-18
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