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Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis

The tumor suppressor p53 plays a critical part in determining cell fate both as a regulator of the transcription of several proapoptotic genes and through its binding interactions with Bcl-2 family proteins at mitochondria. We now demonstrate that p53 protein levels are increased in infected brains...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Zhuang, Yonghua, Berens-Norman, Heather M., Leser, J. Smith, Clarke, Penny, Tyler, Kenneth L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988164/
https://ncbi.nlm.nih.gov/pubmed/27307572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00583-16
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