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Fas-Mediated Apoptotic Signaling in the Mouse Brain following Reovirus Infection
Type 3 (T3) reovirus strains induce apoptotic neuronal cell death and lethal encephalitis in infected mice. T3 strain Dearing (T3D)-induced apoptosis in primary neuronal cultures occurs by a Fas-mediated mechanism and requires the activation of caspase 8. We now show that Fas mRNA is upregulated in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687381/ https://ncbi.nlm.nih.gov/pubmed/19321603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02488-08 |
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