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Fas-Mediated Apoptotic Signaling in the Mouse Brain following Reovirus Infection

Type 3 (T3) reovirus strains induce apoptotic neuronal cell death and lethal encephalitis in infected mice. T3 strain Dearing (T3D)-induced apoptosis in primary neuronal cultures occurs by a Fas-mediated mechanism and requires the activation of caspase 8. We now show that Fas mRNA is upregulated in...

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Hlavní autoři: Clarke, Penny, Beckham, J. David, Leser, J. Smith, Hoyt, Cristen C., Tyler, Kenneth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687381/
https://ncbi.nlm.nih.gov/pubmed/19321603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02488-08
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