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Death Receptor-Mediated Apoptotic Signaling Is Activated in the Brain following Infection with West Nile Virus in the Absence of a Peripheral Immune Response

Apoptosis is an important mechanism of West Nile virus (WNV) pathogenesis within the central nervous system (CNS). The signaling pathways that result in WNV-induced apoptotic neuronal death within the CNS have not been established. In this study, we identified death receptor (DR)-induced apoptosis a...

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Autors principals: Clarke, Penny, Leser, J. Smith, Quick, Eamon D., Dionne, Kalen R., Beckham, J. David, Tyler, Kenneth L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911655/
https://ncbi.nlm.nih.gov/pubmed/24198425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02944-13
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