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Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection

Reovirus encephalitis in mice was used as a model system to investigate astrocyte activation (astrogliosis) following viral infection of the brain. Reovirus infection resulted in astrogliosis, as evidenced by increased expression of glial fibrillary acidic protein (GFAP), and the upregulation of gen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Clarke, Penny, Zhuang, Yonghua, Berens, Heather M., Leser, J. Smith, Tyler, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498044/
https://ncbi.nlm.nih.gov/pubmed/30814290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02027-18
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