A stromal lysolipid-autotaxin signaling axis promotes pancreatic tumor progression

Pancreatic ductal adenocarcinoma (PDAC) develops a pronounced stromal response reflecting an aberrant wound-healing process. This stromal reaction features trans-differentiation of tissue-resident pancreatic stellate cells (PSCs) into activated cancer-associated fibroblasts (CAFs), a process induced...

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書誌詳細
出版年:Cancer Discov
主要な著者: Auciello, Francesca R., Bulusu, Vinay, Oon, Chet, Tait-Mulder, Jacqueline, Berry, Mark, Bhattacharyya, Sohinee, Tumanov, Sergey, Allen-Petersen, Brittany L., Link, Jason, Kendsersky, Nicholas D., Vringer, Esmee, Schug, Michelle, Novo, David, Hwang, Rosa F., Evans, Ronald M., Nixon, Colin, Dorrell, Craig, Morton, Jennifer P., Norman, Jim C., Sears, Rosalie C., Kamphorst, Jurre J., Sherman, Mara H.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497553/
https://ncbi.nlm.nih.gov/pubmed/30837243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1212
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