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The global clonal complexity of the murine blood system declines throughout life and after serial transplantation

Although many recent studies describe the emergence and prevalence of “clonal hematopoiesis of indeterminate potential” in aged human populations, a systematic analysis of the numbers of clones supporting steady-state hematopoiesis throughout mammalian life is lacking. Previous efforts relied on tra...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Ganuza, Miguel, Hall, Trent, Finkelstein, David, Wang, Yong-Dong, Chabot, Ashley, Kang, Guolian, Bi, Wenjian, Wu, Gang, McKinney-Freeman, Shannon
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497513/
https://ncbi.nlm.nih.gov/pubmed/30782612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-873059
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