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Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Understanding the molecular regulation of hematopoietic stem and progenitor cell (HSPC) engraftment is paramount to improving transplant outcomes. To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-transduced HSPCs within 24 h of isolation and transduction t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Holmfeldt, Per, Ganuza, Miguel, Marathe, Himangi, He, Bing, Hall, Trent, Kang, Guolian, Moen, Joseph, Pardieck, Jennifer, Saulsberry, Angelica C., Cico, Alba, Gaut, Ludovic, McGoldrick, Daniel, Finkelstein, David, Tan, Kai, McKinney-Freeman, Shannon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813668/
https://ncbi.nlm.nih.gov/pubmed/26880577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150806
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