Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Understanding the molecular regulation of hematopoietic stem and progenitor cell (HSPC) engraftment is paramount to improving transplant outcomes. To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-transduced HSPCs within 24 h of isolation and transduction t...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Holmfeldt, Per, Ganuza, Miguel, Marathe, Himangi, He, Bing, Hall, Trent, Kang, Guolian, Moen, Joseph, Pardieck, Jennifer, Saulsberry, Angelica C., Cico, Alba, Gaut, Ludovic, McGoldrick, Daniel, Finkelstein, David, Tan, Kai, McKinney-Freeman, Shannon
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813668/
https://ncbi.nlm.nih.gov/pubmed/26880577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150806
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