Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Understanding the molecular regulation of hematopoietic stem and progenitor cell (HSPC) engraftment is paramount to improving transplant outcomes. To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-transduced HSPCs within 24 h of isolation and transduction t...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Holmfeldt, Per, Ganuza, Miguel, Marathe, Himangi, He, Bing, Hall, Trent, Kang, Guolian, Moen, Joseph, Pardieck, Jennifer, Saulsberry, Angelica C., Cico, Alba, Gaut, Ludovic, McGoldrick, Daniel, Finkelstein, David, Tan, Kai, McKinney-Freeman, Shannon
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813668/
https://ncbi.nlm.nih.gov/pubmed/26880577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150806
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