Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Understanding the molecular regulation of hematopoietic stem and progenitor cell (HSPC) engraftment is paramount to improving transplant outcomes. To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-transduced HSPCs within 24 h of isolation and transduction t...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Holmfeldt, Per, Ganuza, Miguel, Marathe, Himangi, He, Bing, Hall, Trent, Kang, Guolian, Moen, Joseph, Pardieck, Jennifer, Saulsberry, Angelica C., Cico, Alba, Gaut, Ludovic, McGoldrick, Daniel, Finkelstein, David, Tan, Kai, McKinney-Freeman, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813668/
https://ncbi.nlm.nih.gov/pubmed/26880577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150806
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