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The global clonal complexity of the murine blood system declines throughout life and after serial transplantation

Although many recent studies describe the emergence and prevalence of “clonal hematopoiesis of indeterminate potential” in aged human populations, a systematic analysis of the numbers of clones supporting steady-state hematopoiesis throughout mammalian life is lacking. Previous efforts relied on tra...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ganuza, Miguel, Hall, Trent, Finkelstein, David, Wang, Yong-Dong, Chabot, Ashley, Kang, Guolian, Bi, Wenjian, Wu, Gang, McKinney-Freeman, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497513/
https://ncbi.nlm.nih.gov/pubmed/30782612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-873059
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