Antigen receptor control of methionine metabolism in T cells

Immune activated T lymphocytes modulate the activity of key metabolic pathways to support the transcriptional reprograming and reshaping of cell proteomes that permits effector T cell differentiation. The present study uses high resolution mass spectrometry and metabolic labelling to explore how mur...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sinclair, Linda V, Howden, Andrew JM, Brenes, Alejandro, Spinelli, Laura, Hukelmann, Jens L, Macintyre, Andrew N, Liu, Xiaojing, Thomson, Sarah, Taylor, Peter M, Rathmell, Jeffrey C, Locasale, Jason W, Lamond, Angus I, Cantrell, Doreen A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497464/
https://ncbi.nlm.nih.gov/pubmed/30916644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44210
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