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Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
The complexity and specificity of many forms of signal transduction are widely suspected to require spatial microcompartmentation of protein kinase and phosphatase activities, yet current relevant imaging methods such as phosphorylation-specific antibodies or fluorescent peptide substrates require f...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64972/ https://ncbi.nlm.nih.gov/pubmed/11752448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211566798 |
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