The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death

Reactive oxygen species (ROS) play a key role in development of heart failure but, at a cellular level, their effects range from cytoprotection to induction of cell death. Understanding how this is regulated is crucial to develop novel strategies to ameliorate only the detrimental effects. Here, we...

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Bibliografiska uppgifter
I publikationen:J Mol Cell Cardiol
Huvudupphovsmän: Meijles, Daniel N., Zoumpoulidou, Georgia, Markou, Thomais, Rostron, Kerry A., Patel, Rishi, Lay, Kenneth, Handa, Balvinder S., Wong, Bethany, Sugden, Peter H., Clerk, Angela
Materialtyp: Artigo
Språk:Inglês
Publicerad: Academic Press 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497135/
https://ncbi.nlm.nih.gov/pubmed/30771309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2019.02.006
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