Counteraction of pRb‐dependent protection after extreme hypoxia by elevated ribonucleotide reductase

Abstract.  We have studied hypoxia‐induced cell cycle arrest in human cells where the retinoblastoma tumour suppressor protein (pRb) is either functional (T‐47D and T‐47DHU‐res cells) or abrogated by expression of the HPV18 E7 oncoprotein (NHIK 3025 cells). We have previously found that pRb is depho...

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Publicat a:Cell Prolif
Autors principals: Graff, P., Seim, J., Åmellem, Ø., Arakawa, H., Nakamura, Y., Andersson, K. K., Stokke, T., Pettersen, E. O.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Ltd 2004
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496405/
https://ncbi.nlm.nih.gov/pubmed/15377335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2004.00319.x
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