The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein.

We have studied the role of the oxygen-dependent pyrimidine metabolism in the regulation of cell cycle progression under moderate hypoxia in human cell lines containing functional (T-47D) or non-functional (NHIK 3025, SAOS-2) retinoblastoma gene product (pRB). Under aerobic conditions, pRB exerts it...

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Detalles Bibliográficos
Main Authors: Amellem, O., Sandvik, J. A., Stokke, T., Pettersen, E. O.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150090/
https://ncbi.nlm.nih.gov/pubmed/9528826
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