Counteraction of pRb‐dependent protection after extreme hypoxia by elevated ribonucleotide reductase

Abstract.  We have studied hypoxia‐induced cell cycle arrest in human cells where the retinoblastoma tumour suppressor protein (pRb) is either functional (T‐47D and T‐47DHU‐res cells) or abrogated by expression of the HPV18 E7 oncoprotein (NHIK 3025 cells). We have previously found that pRb is depho...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Graff, P., Seim, J., Åmellem, Ø., Arakawa, H., Nakamura, Y., Andersson, K. K., Stokke, T., Pettersen, E. O.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd 2004
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496405/
https://ncbi.nlm.nih.gov/pubmed/15377335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2004.00319.x
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