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Counteraction of pRb‐dependent protection after extreme hypoxia by elevated ribonucleotide reductase

Abstract.  We have studied hypoxia‐induced cell cycle arrest in human cells where the retinoblastoma tumour suppressor protein (pRb) is either functional (T‐47D and T‐47DHU‐res cells) or abrogated by expression of the HPV18 E7 oncoprotein (NHIK 3025 cells). We have previously found that pRb is depho...

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Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Graff, P., Seim, J., Åmellem, Ø., Arakawa, H., Nakamura, Y., Andersson, K. K., Stokke, T., Pettersen, E. O.
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Ltd 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496405/
https://ncbi.nlm.nih.gov/pubmed/15377335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2004.00319.x
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