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Effects of PI3‐k/Akt short hairpin RNA on proliferation, fibronectin production and synthesis of thrombospondin‐1 and transforming growth factor‐β(1) in glomerular mesangial cells induced by sublytic C5b‐9 complexes
Objectives: To explore proliferation of glomerular mesangial cells (GMC) and secretion of extracelluar matrix (fibronectin induced by sublytic C5b‐9 complexes), and then ascertain the role of phosphatidylinositol 3‐kinase (PI3‐k)/Akt signal pathway in these processes, by using small hairpin RNAs. Ma...
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| Publicat a: | Cell Prolif |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6495855/ https://ncbi.nlm.nih.gov/pubmed/19143766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2008.00575.x |
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