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Systems Modeling of Bortezomib and Dexamethasone Combinatorial Effects on Bone Homeostasis in Multiple Myeloma Patients

Osteolytic bone disease is one of the most debilitating manifestations of multiple myeloma (MM). Bortezomib is a proteasome inhibitor that shows both anticancer and bone anabolic properties and is being evaluated for its positive effects in MM patients with skeletal complications. Dexamethasone is a...

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Vydáno v:J Pharm Sci
Hlavní autoři: Zhang, Li, Mager, Donald E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495529/
https://ncbi.nlm.nih.gov/pubmed/30472266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.11.024
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