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Systems Modeling of Bortezomib and Dexamethasone Combinatorial Effects on Bone Homeostasis in Multiple Myeloma Patients

Osteolytic bone disease is one of the most debilitating manifestations of multiple myeloma (MM). Bortezomib is a proteasome inhibitor that shows both anticancer and bone anabolic properties and is being evaluated for its positive effects in MM patients with skeletal complications. Dexamethasone is a...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Zhang, Li, Mager, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495529/
https://ncbi.nlm.nih.gov/pubmed/30472266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.11.024
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