Overexpression of Nudt7 decreases bile acid levels and peroxisomal fatty acid oxidation in the liver

Lipid metabolism requires CoA, an essential cofactor found in multiple subcellular compartments, including the peroxisomes. In the liver, CoA levels are dynamically adjusted between the fed and fasted states. Elevated CoA levels in the fasted state are driven by increased synthesis; however, this al...

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Bibliografiska uppgifter
I publikationen:J Lipid Res
Huvudupphovsmän: Shumar, Stephanie A., Kerr, Evan W., Fagone, Paolo, Infante, Aniello M., Leonardi, Roberta
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495166/
https://ncbi.nlm.nih.gov/pubmed/30846528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M092676
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