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Overexpression of PGC-1α increases peroxisomal activity and mitochondrial fatty acid oxidation in human primary myotubes

Peroxisomes are indispensable organelles for lipid metabolism in humans, and their biogenesis has been assumed to be under regulation by peroxisome proliferator-activated receptors (PPARs). However, recent studies in hepatocytes suggest that the mitochondrial proliferator PGC-1α (peroxisome prolifer...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Huang, Tai-Yu, Zheng, Donghai, Houmard, Joseph A., Brault, Jeffrey J., Hickner, Robert C., Cortright, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406987/
https://ncbi.nlm.nih.gov/pubmed/28073778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00331.2016
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