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Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase
Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalyzed reactions. Isotopically labeled l-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltransf...
Guardat en:
| Publicat a: | J Lipid Res |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6495160/ https://ncbi.nlm.nih.gov/pubmed/30792183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M089367 |
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