Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

BACKGROUND: Lipoprotein(a) [Lp(a)], a major carrier of oxidized phospholipids (OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it remains unclear whether elevated Lp(a) and OxPL drive disease progression and are therefore targets for therapeutic intervention. OBJEC...

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Bibliografiska uppgifter
I publikationen:J Am Coll Cardiol
Huvudupphovsmän: Zheng, Kang H., Tsimikas, Sotirios, Pawade, Tania, Kroon, Jeffrey, Jenkins, William S.A., Doris, Mhairi K., White, Audrey C., Timmers, Nyanza K.L.M., Hjortnaes, Jesper, Rogers, Maximillian A., Aikawa, Elena, Arsenault, Benoit J., Witztum, Joseph L., Newby, David E., Koschinsky, Marlys L., Fayad, Zahi A., Stroes, Erik S.G., Boekholdt, S. Matthijs, Dweck, Marc R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Biomedical 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494952/
https://ncbi.nlm.nih.gov/pubmed/31047003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.070
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