Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a)

Lipoprotein (a) [Lp(a)] is a risk factor for CVD and a target of therapy, but Lp(a) measurements are not globally standardized. Commercially available assays generally use polyclonal antibodies that detect multiple sites within the kringle (K)IV(2) repeat region of Lp(a) and may lead to inaccurate a...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Gonen, Ayelet, Yang, Xiaohong, Yeang, Calvin, Alekseeva, Elena, Koschinsky, Marlys, Witztum, Joseph L., Boffa, Michael, Tsimikas, Sotirios
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469883/
https://ncbi.nlm.nih.gov/pubmed/32641432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000830
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