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Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a)

Lipoprotein (a) [Lp(a)] is a risk factor for CVD and a target of therapy, but Lp(a) measurements are not globally standardized. Commercially available assays generally use polyclonal antibodies that detect multiple sites within the kringle (K)IV(2) repeat region of Lp(a) and may lead to inaccurate a...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Gonen, Ayelet, Yang, Xiaohong, Yeang, Calvin, Alekseeva, Elena, Koschinsky, Marlys, Witztum, Joseph L., Boffa, Michael, Tsimikas, Sotirios
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469883/
https://ncbi.nlm.nih.gov/pubmed/32641432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000830
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