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Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a)

Lipoprotein (a) [Lp(a)] is a risk factor for CVD and a target of therapy, but Lp(a) measurements are not globally standardized. Commercially available assays generally use polyclonal antibodies that detect multiple sites within the kringle (K)IV(2) repeat region of Lp(a) and may lead to inaccurate a...

詳細記述

保存先:
書誌詳細
出版年:J Lipid Res
主要な著者: Gonen, Ayelet, Yang, Xiaohong, Yeang, Calvin, Alekseeva, Elena, Koschinsky, Marlys, Witztum, Joseph L., Boffa, Michael, Tsimikas, Sotirios
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469883/
https://ncbi.nlm.nih.gov/pubmed/32641432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000830
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