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Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein (a)

Lipoprotein (a) [Lp(a)] is a risk factor for CVD and a target of therapy, but Lp(a) measurements are not globally standardized. Commercially available assays generally use polyclonal antibodies that detect multiple sites within the kringle (K)IV(2) repeat region of Lp(a) and may lead to inaccurate a...

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Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Gonen, Ayelet, Yang, Xiaohong, Yeang, Calvin, Alekseeva, Elena, Koschinsky, Marlys, Witztum, Joseph L., Boffa, Michael, Tsimikas, Sotirios
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469883/
https://ncbi.nlm.nih.gov/pubmed/32641432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000830
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