Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

BACKGROUND: Lipoprotein(a) [Lp(a)], a major carrier of oxidized phospholipids (OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it remains unclear whether elevated Lp(a) and OxPL drive disease progression and are therefore targets for therapeutic intervention. OBJEC...

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書誌詳細
出版年:J Am Coll Cardiol
主要な著者: Zheng, Kang H., Tsimikas, Sotirios, Pawade, Tania, Kroon, Jeffrey, Jenkins, William S.A., Doris, Mhairi K., White, Audrey C., Timmers, Nyanza K.L.M., Hjortnaes, Jesper, Rogers, Maximillian A., Aikawa, Elena, Arsenault, Benoit J., Witztum, Joseph L., Newby, David E., Koschinsky, Marlys L., Fayad, Zahi A., Stroes, Erik S.G., Boekholdt, S. Matthijs, Dweck, Marc R.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Biomedical 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494952/
https://ncbi.nlm.nih.gov/pubmed/31047003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.070
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