Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids

Previous studies have utilized monoamine oxidase (MAO) and L-3,4-dihydroxyphenylalanine decarboxylase (DDC) for microbe-based production of tetrahydropapaveroline (THP), a benzylisoquinoline alkaloid (BIA) precursor to opioid analgesics. In the current study, a phylogenetically distinct Bombyx mori...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Vavricka, Christopher J., Yoshida, Takanobu, Kuriya, Yuki, Takahashi, Shunsuke, Ogawa, Teppei, Ono, Fumie, Agari, Kazuko, Kiyota, Hiromasa, Li, Jianyong, Ishii, Jun, Tsuge, Kenji, Minami, Hiromichi, Araki, Michihiro, Hasunuma, Tomohisa, Kondo, Akihiko
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494836/
https://ncbi.nlm.nih.gov/pubmed/31043610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09610-2
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