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Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

The benzylisoquinoline alkaloids (BIAs) are a diverse class of metabolites that exhibit a broad range of pharmacological activities and are synthesized through plant biosynthetic pathways comprised of complex enzyme activities and regulatory strategies. We have engineered yeast to produce the key in...

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Detalhes bibliográficos
Main Authors: Hawkins, Kristy M, Smolke, Christina D
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830865/
https://ncbi.nlm.nih.gov/pubmed/18690217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.105
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