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De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast

Microbial biosynthesis for plant-based natural products, such as the benzylisoquinoline alkaloids (BIAs), has the potential to address limitations in plant-based supply of established drugs and make new molecules available for drug discovery. While yeast strains have been engineered to produce a var...

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Bibliografiske detaljer
Udgivet i:Metab Eng
Main Authors: Trenchard, Isis J., Siddiqui, Michael S., Thodey, Kate, Smolke, Christina D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575844/
https://ncbi.nlm.nih.gov/pubmed/26166409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2015.06.010
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