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Complete biosynthesis of opioids in yeast

Opioids are the primary drugs used in Western medicine for pain management and palliative care. Farming of opium poppies remains the sole source of these essential medicines despite diverse market demands and uncertainty in crop yields due to weather, climate change, and pests. Here, we engineered y...

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Bibliographic Details
Published in:Science
Main Authors: Galanie, Stephanie, Thodey, Kate, Trenchard, Isis J., Interrante, Maria Filsinger, Smolke, Christina D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924617/
https://ncbi.nlm.nih.gov/pubmed/26272907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9373
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