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Complete biosynthesis of opioids in yeast

Opioids are the primary drugs used in Western medicine for pain management and palliative care. Farming of opium poppies remains the sole source of these essential medicines despite diverse market demands and uncertainty in crop yields due to weather, climate change, and pests. Here, we engineered y...

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Publicado en:Science
Main Authors: Galanie, Stephanie, Thodey, Kate, Trenchard, Isis J., Interrante, Maria Filsinger, Smolke, Christina D.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924617/
https://ncbi.nlm.nih.gov/pubmed/26272907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9373
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