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Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of methylenetetrahydrofolate to methyltetrahydrofolate, the major methyl donor for the conversion of homocysteine to methionine. Two common polymorphisms of the human enzyme have been identified: 677C>T, which leads to the subst...

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Autori principali: Yamada, Kazuhiro, Chen, Zhoutao, Rozen, Rima, Matthews, Rowena G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC64948/
https://ncbi.nlm.nih.gov/pubmed/11742092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261469998
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