Regulation of human methylenetetrahydrofolate reductase by phosphorylation

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of methylenetetrahydrofolate to methyltetrahydrofolate, the methyl donor for the conversion of homocysteine to methionine. Regulation of MTHFR activity is crucial for maintaining cellular concentrations of methionine and S-adenosylm...

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Bibliographic Details
Main Authors: Yamada, Kazuhiro, Strahler, John R., Andrews, Philip C., Matthews, Rowena G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180802/
https://ncbi.nlm.nih.gov/pubmed/16024724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504786102
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