Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia.

A common missense mutation in the methylenetetrahydrofolate reductase (MTHFR) gene, a C to T substitution at nucleotide 677, is responsible for reduced MTHFR activity and associated with modestly increased plasma homocysteine concentrations. Since underlying maternal vascular disease increases the r...

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Bibliografiske detaljer
Main Authors: Sohda, S, Arinami, T, Hamada, H, Yamada, N, Hamaguchi, H, Kubo, T
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050983/
https://ncbi.nlm.nih.gov/pubmed/9192280
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