Protein Phosphatase 1 Inhibitor–1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter

BACKGROUND: A number of cAMP-elevating hormones stimulate phosphorylation (and hence activity) of the NaCl cotransporter (NCC) in the distal convoluted tubule (DCT). Evidence suggests that protein phosphatase 1 (PP1) and other protein phosphatases modulate NCC phosphorylation, but little is known ab...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Penton, David, Moser, Sandra, Wengi, Agnieszka, Czogalla, Jan, Rosenbaek, Lena Lindtoft, Rigendinger, Fritz, Faresse, Nourdine, Martins, Joana R., Fenton, Robert A., Loffing-Cueni, Dominique, Loffing, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493980/
https://ncbi.nlm.nih.gov/pubmed/30902838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018050540
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