P2X7 Receptor Inhibition Interrupts the Progression of Seizures in Immature Rats and Reduces Hippocampal Damage

AIMS: Early‐life seizures, particularly when prolonged, may be harmful to the brain. Current pharmacotherapy is often ineffective; therefore, novel neuro‐ and/or glio‐transmitter systems should be explored for targeting. The P2X7 receptor is a cation‐permeable channel with trophic and excitability e...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Mesuret, Guillaume, Engel, Tobias, Hessel, Ellen V., Sanz‐Rodriguez, Amaya, Jimenez‐Pacheco, Alba, Miras‐Portugal, M. Teresa, Diaz‐Hernandez, Miguel, Henshall, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493144/
https://ncbi.nlm.nih.gov/pubmed/24750893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12272
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