Φορτώνει......
Hyperglycemia Increases the Production of Amyloid Beta‐Peptide Leading to Decreased Endothelial Tight Junction
AIMS: Amyloid beta‐peptide (Aβ), the main component of senile plaques in the Alzheimer's disease (AD) brains, is generated from sequential cleavage of amyloid precursor protein (APP) by β‐ and γ‐secretase. Hyperglycemia in diabetes may compromise barrier integrity in endothelial cells (ECs). Ho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | CNS Neurosci Ther |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492831/ https://ncbi.nlm.nih.gov/pubmed/26842741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12503 |
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