Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity

Alzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by excessive beta amyloid (Aβ) deposition in brain, leading to blood–brain barrier (BBB) disruption. The mechanisms of BBB disruption in AD are still unclear, despite considerable research. The adipokine adiponectin...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Song, Juhyun, Choi, Seong-Min, Whitcomb, Daniel J, Kim, Byeong C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682657/
https://ncbi.nlm.nih.gov/pubmed/29022894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.491
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