Tim-3 promotes tube formation and decreases tight junction formation in vascular endothelial cells

As a negative immune checkpoint molecule, T-cell immunoglobulin domain and mucin domain containing molecule-3 (Tim-3) has been found to serve a crucial role in immune escape and tumour progression. Previous studies have reported that Tim-3 is important to endothelial cells and it has also been demon...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Cong, Yizi, Wang, Xingmiao, Wang, Suxia, Qiao, Guangdong, Li, Yalun, Cao, Jianqiao, Jiang, Wenguo, Cui, Yuxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2020
Schlagworte:
Cardiovascular System & Vascular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560514/
https://ncbi.nlm.nih.gov/pubmed/33015716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20202130
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