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Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta‐Amyloid Deposition in Mice via BACE1‐Antisense Activation
AIMS: To clarify the correlation between chronic sleep restriction (CSR) and sporadic Alzheimer disease (AD), we determined in wild‐type mice the impact of CSR, on cognitive performance, beta‐amyloid (Aβ) peptides, and its feed‐forward regulators regarding AD pathogenesis. METHODS: Sixteen nine‐mont...
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| Udgivet i: | CNS Neurosci Ther |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492718/ https://ncbi.nlm.nih.gov/pubmed/28145081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12667 |
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