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Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain Injury

Traumatic brain injury (TBI) leads to both acute injury and long-term neurodegeneration, and is a major risk factor for developing Alzheimer's disease (AD). Beta amyloid (Aβ) peptide deposits in the brain are one of the pathological hallmarks of AD. Aβ levels increase after TBI in animal models...

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Detalhes bibliográficos
Main Authors: Yu, Fengshan, Zhang, Yumin, Chuang, De-Maw
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430485/
https://ncbi.nlm.nih.gov/pubmed/22583494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2449
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