A Humanin Derivative Reduces Amyloid Beta Accumulation and Ameliorates Memory Deficit in Triple Transgenic Mice

Humanin (HN), a 24-residue peptide, was identified as a novel neuroprotective factor and shows anti-cell death activity against a wide spectrum of Alzheimer's disease (AD)-related cytotoxicities, including exposure to amyloid beta (Abeta), in vitro. We previously demonstrated that the injection...

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Detalhes bibliográficos
Main Authors: Niikura, Takako, Sidahmed, Elkhansa, Hirata-Fukae, Chiho, Aisen, Paul S., Matsuoka, Yasuji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022031/
https://ncbi.nlm.nih.gov/pubmed/21264226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016259
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