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Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition
Reticulon 3 (RTN3) has previously been shown to interact with BACE1 and negatively regulate BACE1 activity. To what extent RTN3 deficiency affects BACE1 activity is an intriguing question. In this study, we aimed to address this by generating RTN3-null mice. Mice with complete deficiency of RTN3 gro...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198539/ https://ncbi.nlm.nih.gov/pubmed/25319692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1588-14.2014 |
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