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Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition
Reticulon 3 (RTN3) has previously been shown to interact with BACE1 and negatively regulate BACE1 activity. To what extent RTN3 deficiency affects BACE1 activity is an intriguing question. In this study, we aimed to address this by generating RTN3-null mice. Mice with complete deficiency of RTN3 gro...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198539/ https://ncbi.nlm.nih.gov/pubmed/25319692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1588-14.2014 |
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