The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae

BACKGROUND: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malignant tumours in many organ systems, including renal cysts and clear cell renal cell carcinoma. It is not completely understood what underlies the development of renal pathology, and the use of murine V...

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發表在:Nephron Clin Pract
Main Authors: van Rooijen, Ellen, van de Hoek, Glenn, Logister, Ive, Ajzenberg, Henry, Knoers, Nine V.A.M., van Eeden, Freek, Voest, Emile E., Schulte-Merker, Stefan, Giles, Rachel H.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2018
主題:
Experimental Nephrology and Genetics: Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492518/
https://ncbi.nlm.nih.gov/pubmed/29342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484096
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