The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae

BACKGROUND: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malignant tumours in many organ systems, including renal cysts and clear cell renal cell carcinoma. It is not completely understood what underlies the development of renal pathology, and the use of murine V...

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Publicat a:Nephron Clin Pract
Autors principals: van Rooijen, Ellen, van de Hoek, Glenn, Logister, Ive, Ajzenberg, Henry, Knoers, Nine V.A.M., van Eeden, Freek, Voest, Emile E., Schulte-Merker, Stefan, Giles, Rachel H.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2018
Matèries:
Experimental Nephrology and Genetics: Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492518/
https://ncbi.nlm.nih.gov/pubmed/29342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484096
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