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The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae

BACKGROUND: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malignant tumours in many organ systems, including renal cysts and clear cell renal cell carcinoma. It is not completely understood what underlies the development of renal pathology, and the use of murine V...

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Publicado en:Nephron Clin Pract
Main Authors: van Rooijen, Ellen, van de Hoek, Glenn, Logister, Ive, Ajzenberg, Henry, Knoers, Nine V.A.M., van Eeden, Freek, Voest, Emile E., Schulte-Merker, Stefan, Giles, Rachel H.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492518/
https://ncbi.nlm.nih.gov/pubmed/29342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484096
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