The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae

BACKGROUND: von Hippel-Lindau (VHL) disease is characterized by the development of benign and malignant tumours in many organ systems, including renal cysts and clear cell renal cell carcinoma. It is not completely understood what underlies the development of renal pathology, and the use of murine V...

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Détails bibliographiques
Publié dans:Nephron Clin Pract
Auteurs principaux: van Rooijen, Ellen, van de Hoek, Glenn, Logister, Ive, Ajzenberg, Henry, Knoers, Nine V.A.M., van Eeden, Freek, Voest, Emile E., Schulte-Merker, Stefan, Giles, Rachel H.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2018
Sujets:
Experimental Nephrology and Genetics: Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492518/
https://ncbi.nlm.nih.gov/pubmed/29342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484096
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