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Narrowing the field: cancer-specific promoters for mitochondrially-targeted p53-BH3 fusion gene therapy in ovarian cancer

BACKGROUND: Despite years of research, the treatment options and mortality rate for ovarian cancer remain relatively stagnant. Resistance to chemotherapy and high heterogeneity in mutations contribute to ovarian cancer’s lethality, including many mutations in tumor suppressor p53. Though wild type p...

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Pubblicato in:J Ovarian Res
Autori principali: Bowman, Katherine Redd, Kim, Ji Hoon, Lim, Carol S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492428/
https://ncbi.nlm.nih.gov/pubmed/31039796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-019-0514-4
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