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Narrowing the field: cancer-specific promoters for mitochondrially-targeted p53-BH3 fusion gene therapy in ovarian cancer

BACKGROUND: Despite years of research, the treatment options and mortality rate for ovarian cancer remain relatively stagnant. Resistance to chemotherapy and high heterogeneity in mutations contribute to ovarian cancer’s lethality, including many mutations in tumor suppressor p53. Though wild type p...

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Detalhes bibliográficos
Publicado no:J Ovarian Res
Main Authors: Bowman, Katherine Redd, Kim, Ji Hoon, Lim, Carol S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492428/
https://ncbi.nlm.nih.gov/pubmed/31039796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-019-0514-4
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