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Association of p53 and mitochondrial gene with chemosensitization by metformin in ovarian cancer

OBJECTIVE: This study aims to investigate the association of p53 and D-loop gene with drug resistance and sensitization induced by metformin in ovarian cancer. RESULTS: Metformin suppresses cells in a time-dependent manner, but the inhibition does not change with the dose of metformin. This suggests...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wei, De-Hua, Wang, Yan, Shi, Hui-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790438/
https://ncbi.nlm.nih.gov/pubmed/29423021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22863
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