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Dexamethasone and dexamethasone-phosphate entry into perilymph compared for middle ear applications in guinea pigs.

Dexamethasone-phosphate is widely used for intratympanic therapy in humans. We assessed the pharmacokinetics of dexamethasone entry into perilymph when administered as dexamethasone-phosphate solution or as a micronized dexamethasone suspension, with and without inclusion of poloxamer gel in the med...

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Détails bibliographiques
Publié dans:Audiol Neurootol
Auteurs principaux: Salt, Alec N., Hartsock, Jared J., Piu, Fabrice, Hou, Jennifer
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492027/
https://ncbi.nlm.nih.gov/pubmed/30497073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000493846
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